Recent Trends in Advanced Biosensors for Early Detection of Fungal Spoilage and Intoxication in Food of Animal Origin
DOI:
https://doi.org/10.33687/ricosbiol.03.08.68Keywords:
Mycotoxins, milk, meat, food safety, biosensorsAbstract
The public health concern induced by mycotoxins contamination has globally retained a prominent deal of interest. Mycotoxins are secondarily synthetized and can accumulate in host organs so institute adverse effects on humans and livestock, resulting in grave health threats and often produced by certain filamentous fungi broadly found in foodstuffs. Enhancing early trace recognition and control from the root is a more coveted approach than the disposal way to assert food safety. Biosensors are ready to interference from various components in intricate food matrices when recognizing trace mycotoxins. This article focuses on advanced approaches especially incorporation of biosensors for detection of mycotoxins in food matrices of animal origin as well as progressing of sensing detection for food safety assurance.
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Ahmadi SF, Hojjatoleslamy M, Kiani H and Molavi H. (2022) Monitoring of Aflatoxin M1 in milk using a novel electrochemicalaptasensorbased on reduced graphene oxide and gold nanoparticles. Food Chem. 30,373(Pt A):131321.
Angelopoulou M, Kourti D, Misiakos K, Economou A, Petrou Pand Kakabakos S. (2023). Mach-Zehnder Interferometric Immunosensor for Detection of Aflatoxin M1 in Milk, Chocolate Milk, and Yogurt. Biosensors (Basel). 30,13(6),592.
Badawy M.E.I., El-Nouby M.A.M., Kimani P.K., Lim L.W. and Rabea E.I. (2022). A review of the modern principles and applications of solid-phase extraction techniques in chromatographic analysis. Anal. Sci.,38,1457–1487.
Bian Y., Zhang Y., Zhou Y., Wei B. and Feng X. (2023). Recent Insights into Sample Pretreatment Methods for Mycotoxins in Different Food Matrices: A Critical Review on Novel Materials. Toxins, 15,215.
Díaz-Bao M, Regal P, Barreiro R, Fente CA. and Cepeda A. (2016). A facile method for the fabrication of magnetic molecularly imprinted stir-bars: A practical example with aflatoxins in baby foods. J Chromatogr A., 1471,51-59.
Eid S., Gehad F.A. Fath Elbab , Amany N. Dapgh, Hakim A. S., Wagdy S.B. Youssef and Hussien A. Abouelhag. (2025). Food Contact Material (FCM) Migration Testing: Novel Assay for Ensuring Food Safety. Ricos Biology Journal, Vol. 3 (7) 12-16.
El-Sayed R., Jebur A., Kang W., El-Esawi M. and El-Demerdash F. (2020). An overview on the major mycotoxins in food products: Characteristics, toxicity, and analysis. J. Future Foods, 2,91–102.
Gaudin V. (2017). Advances in biosensor development for the screening of antibiotic residues in food products of animal origin—A comprehensive review. Biosens. Bioelectron, 90,363–377. Yang Y., Li G., Wu D., Liu J., Li X., Luo P., Hu N., Wang H. and Wu Y. (2020). Recent advances on toxicity and determination methods of mycotoxins in foodstuffs. Trends Food Sci. Technol, 96,233–252.
Haque M.A., Wang Y., Shen Z., Li X., Saleemi M.K. and He C. (2020). Mycotoxin contamination and control strategy in human, domestic animal and poultry: A review. Microb. Pathog., 142,104095.
Janik E., Niemcewicz M., Ceremuga M., Stela M., Saluk-Bijak J., Siadkowski A. and Bijak M. (2020). Molecular Aspects of Mycotoxins—A Serious Problem for Human Health. Int. J. Mol. Sci., 21,8187.
Jia M., Jia B., Liao X., Shi L., Zhang Z., Liu M., Zhou L., Li D. and Kong W. (2022). A CdSe@CdS quantum dots based electrochemiluminescence aptasensor for sensitive detection of ochratoxin A. Chemosphere, 287,131994.
Li M., Yue Q., Fang J., Wang C., Cao W. and Wei Q. (2022). Au modified spindle-shaped cerium phosphate as an efficient co-reaction accelerator to amplify electrochemiluminescence signal of carbon quantum dots for ultrasensitive analysis of aflatoxin B1. Electrochim. Acta., 407,139912.
Lizakowski P K.A. (2019). Legal regulations and administration of food safety. World Sci. News., 122,133–144.
Lu S., Li G., Lv Z., Qiu N., Kong W., Gong P., Chen G., Xia L., Guo X., You J. and et al. (2016). Facile and ultrasensitive fluorescence sensor platform for tumor invasive biomarker beta-glucuronidase detection and inhibitor evaluation with carbon quantum dots based on inner-filter effect. Biosens. Bioelectron, 85,358–362.
Lv X., Tan F., Miao T., Cui B., Zhang J., Fang Y. and Shen Y. (2023). In situ generated PtNPs to enhance electrochemiluminescence of multifunctional nanoreactor COP T(4)VTP(6) for AFB(1) detection. Food Chem., 399,134002.
Maggira M, Sakaridis I, Ioannidou M and Samouris G. (2022). Comparative Evaluation of Three Commercial Elisa Kits Used for the Detection of Aflatoxins B1, B2, G1, and G2 in Feedstuffs and Comparison with an HPLC Method. Vet Sci., 9(3),104.
Meyers C.L.F. and Meyers D.J. (2008). Thin-Layer Chromatography. Curr. Protoc. Nucleic Acid. Chem., 34, A.3D.1–A.3D.13.
Nakhjavan B., Ahmed N.S. and Khosravifard M. (2020). Development of an improved method of sample extraction and quantitation of multi-mycotoxin in feed by LC-MS/MS. Toxins, 12,462.
Naz I, Alanazi SJF, Hayat A and Jubeen F. (2025). Covalent organic framework-based aptananozyme (COF@NH2 apt-AFM1): A novel platform for colorimetric and fluorescent aptasensing of AFM1 in milk. Food Chem., 484,144478.
Pandey A.K., Samota M.K., Kumar A., Silva A.S. and Dubey N.K. (2023). Fungal mycotoxins in food commodities: Present status and future concerns. Front. Sustain. Food Syst., 7,1162595.
Pereira V., Fernandes J. and Cunha S. (2015). Comparative assessment of three cleanup procedures after QuEChERS extraction for determination of trichothecenes (type A and type B) in processed cereal-based baby foods by GC–MS. Food Chem., 182,143–149.
Ramezani M, Jalalian SH, Taghdisi SM, Abnous K and Alibolandi M. (2022). Optical and Electrochemical Aptasensors for Sensitive Detection of Aflatoxin B1 and Aflatoxin M1 in Blood Serum, Grape Juice, and Milk Samples. Methods Mol Biol., 2393,417-436.
Rodríguez-Carrasco Y., Moltó J.C., Berrada H. and Mañes J. (2014). A survey of trichothecenes, zearalenone and patulin in milled grain-based products using GC–MS/MS. Food Chem.,146,212–219.
Singh H, Singh S, Bhardwaj SK, Kaur G, Khatri M, Deep A and Bhardwaj N. (2022). Development of carbon quantum dot-based lateral flow immunoassay for sensitive detection of aflatoxin M1 in milk. Food Chem., 1 393,133374.
Sorbo A., Pucci E., Nobili C., Taglieri I., Passeri D. and Zoani C. (2022). Food Safety Assessment: Overview of Metrological Issues and Regulatory Aspects in the European Union. Separations, 9,53.
Sosnowski M. and Osek J. (2021). Microbiological Safety of Food of Animal Origin from Organic Farms. J. Vet. Res., 65,87–92.
Sun Y, Lv Y, Zhang Y and Wang Z. (2023). A stimuli-responsive colorimetric aptasensor based on the DNA hydrogel-coated MOF for fumonisin B1 determination in food samples. Food Chem., 403,134242.
Szelenberger R, Cichoń N, Zajaczkowski W and Bijak M. (2024). Application of Biosensors for the Detection of Mycotoxins for the Improvement of Food Safety. Toxins (Basel), 27 16(6),249.
Turner N.W., Subrahmanyam S. and Piletsky S.A. (2009). Analytical methods for determination of mycotoxins: A review. Anal. Chim. Acta, 632,168–180.
Ventura M, Anaya I, Broto-Puig F, Agut M and Comellas L. (2005). Two-dimensional thin-layer chromatographic method for the analysis of ochratoxin A in green coffee. J Food Prot., 68(9),1920-2.
Wang Y, Zhang L, Peng D, Xie S, Chen D, Pan Y, Tao Y and Yuan Z. (2018). Construction of Electrochemical Immunosensor Based on Gold-Nanoparticles/Carbon Nanotubes/Chitosan for Sensitive Determination of T-2 Toxin in Feed and Swine Meat. Int J Mol Sci., 19(12),3895.
Yugender Goud K., Sunil Kumar V., Hayat A., Vengatajalabathy Gobi K., Song H., Kim K.-H. and Marty J.L. (2019). A highly sensitive electrochemical immunosensor for zearalenone using screen-printed disposable electrodes. J. Electroanal. Chem., 832,336–342.
Zhang L., Dou X.-W., Zhang C., Logrieco A.F. and Yang M.-H. (2018). A review of current methods for analysis of mycotoxins in herbal medicines. Toxins, 10,65.
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Copyright (c) 2025 Samah Eid , Elsayed S.E. Shabana, Amany N. Dapgh, Ahmed Shabaan, Ali Amer, Asmaa E. Gamal El-deen, Wagdy S. B. Youssef, Ashraf S. Hakim, Abouelhag H. A.
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