Food Contact Material (FCM) Migration Testing; Novel Assay for Ensuring Food Safety

Authors

  • Samah Eid Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center (ARC), Giza, Egypt.
  • Gehad F.A. Fath Elbab Department of Food Hygiene, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt
  • Amany N. Dapgh Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.
  • Ashraf S. Hakim Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.
  • Wagdy Samir Beshir Youssef Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.
  • Hussien A. Abouelhag Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.

DOI:

https://doi.org/10.33687/ricosbiol.03.07.66

Keywords:

Food Contact Materials, Food Safety, Chemical Migration, Migration Testing, Non-Intentionally Added Substances (NIAS)

Abstract

The safety of food is fundamental, and a pivotal aspect of this is the prospect for chemical substances to transmit from food contact materials (FCMs) into food. This approach, known as migration, can drive harmful compounds, change food quality, and institute a risk to human health. Consequently, migration testing of FCMs is a crucial component of food safety regulations globally. This article furnishes a comprehensive overview of FCM migration assay, comprising its primary principles, the analytical procedures utilized, and the global food safety standards that control it. It also discusses neoteric research trends, compliances, and, highlighting the developing nature of this critical field.

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Author Biographies

  • Samah Eid, Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center (ARC), Giza, Egypt.

    Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center (ARC), Giza, Egypt.

  • Gehad F.A. Fath Elbab, Department of Food Hygiene, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt

    Department of Food Hygiene, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt

  • Amany N. Dapgh, Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.
    Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.
  • Ashraf S. Hakim, Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.

    Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.

  • Wagdy Samir Beshir Youssef, Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.

    Department of Bacteriology, Animal Health Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.

  • Hussien A. Abouelhag, Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.

    Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt.

References

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European Union. Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with food.

Food and Drug Administration (FDA). Title 21 Code of Federal Regulations (21 CFR) Part 170-199, various parts related to food additives and food contact substances.

Geueke, B., Groh, K., and Muncke, J. (2018). Food packaging in the circular economy: Are food contact chemicals an obstacle? Environmental Science & Technology, 52(18), 10966-10978.

Groh M. E. et al., (2018). "Assessing the hazards of plastic packaging: A global review," Chemosphere, 209, 297-306.

Gupta, S., Kumar, R., and Singh, R. (2024). Food Packaging and Chemical Migration: A Food Safety Perspective. International Journal of Environmental Research and Public Health, 21(4), 481.

HQTS. (2025). Food Contact Material Testing - How to comply with EU and US regulations. Retrieved from https://www.hqts.com/183186/

Muncke A. et al., (2021). A vision for safer food contact materials: Public health concerns as drivers for improved testing. J. Expo. Sci. Environ. Epidemiol., vol. 31, no. 1, 1-13.

Muncke, J., Myers, J. P., Scheringer, M., and Porta, M. (2020). Food packaging and chemical migration: A food safety perspective. Journal of Environmental Health Perspectives, 128(1), 015001.

Ong S. R. et al., (2020). Perinatal exposure to nonylphenol and obesity risk in offspring. Environ. Pollut., 261.

Paseiro-Cerrato M. C. et al., (2006) "Compilation of analytical methods for model migrants in foodstuffs," European Commission, Joint Research Centre.

Paseiro-Cerrato, R., DeJager, L., and Begley, T. H. (2019). Assessment of the Impact of Accelerated Migration Testing for Coated Food Cans Using Food Simulants. Molecules, 24(17), 3123.

Regulation (EC) No 1935/2004 of the European Parliament and of the Council of 27 October 2004 on materials and articles intended to come into contact with food.

Urbelis, S., and Cooper, L. V. (2021). Migration of food contact substances into dry foods: A review. Food Additives & Contaminants: Part A, 38(3), 473-492.

Seref, N., and Cufaoglu, G. (2025). Food Packaging and Chemical Migration: A Food Safety Perspective. Journal of food science, 90(5), e70265. https://doi.org/10.1111/1750-3841.70265

Ricos Biology Journal (2025), 3(7), 12-16.

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Published

22-07-2025

Data Availability Statement

Ricos Biology Journal

Issue

Vol. 3 No. 7 (2025): RICOS BIOLOGY JOURNAL

Section

Review Articles

Categories

License

Copyright (c) 2025 Samah Eid, Gehad F.A. Fath Elbab, Amany N. Dapgh, Ashraf S. Hakim, Wagdy Samir Beshir Youssef, Hussien A. Abouelhag

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

How to Cite

Food Contact Material (FCM) Migration Testing; Novel Assay for Ensuring Food Safety. (2025). Ricos Biology, 3(7), 12-16. https://doi.org/10.33687/ricosbiol.03.07.66

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