A Perfect Storm: The Escalating Crisis of Antimicrobial Resistance in Surgical Wounds in Gaza

Antimicrobial Resistance in Gaza

Authors

  • Hussein Abouelhag Professor of Microbiology and Immunology at Department of Microbiology and Immunology, National Research Centre, Dokki, Giza, Egypt, 12622

DOI:

https://doi.org/10.33687/ricosbiol.03.010.86

Keywords:

antimicrobial resistance, Gaza, surgical site infection, conflict medicine, war wounds, global health security, infection prevention and control, multidrug-resistant organisms

Abstract

The Gaza conflict has precipitated a catastrophic humanitarian crisis, creating an ideal environment for the emergence and spread of antimicrobial resistance (AMR). This review synthesizes evidence from humanitarian reports, medical testimonials, and preliminary data to analyze the multifactorial drivers of AMR in surgical wounds. The collapse of healthcare infrastructure, critical shortages of antibiotics and supplies, the impossibility of infection prevention and control (IPC), and the unique nature of war injuries converge into a perfect storm. With laboratories destroyed and antimicrobial stewardship abandoned, clinicians are forced into empirical, often ineffective antibiotic use, rapidly selecting for resistant pathogens like multidrug-resistant Acinetobacter baumannii. The consequences are increased morbidity, amputations, and mortality for patients, while posing a severe threat to global health security by creating reservoirs of untreatable infections. This review concludes that the situation in Gaza represents a profound failure of medical ethics and international law, demanding urgent, coordinated intervention to prevent a long-term AMR catastrophe.

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Author Biography

  • Hussein Abouelhag, Professor of Microbiology and Immunology at Department of Microbiology and Immunology, National Research Centre, Dokki, Giza, Egypt, 12622
    Department of Microbiology and Immunology, National Research Centre, Dokki, Giza, Egypt, 12622

References

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Karruli, A., D'Atanasio, N., and Durante-Mangoni, E. (2023). Multidrug-resistant Acinetobacter baumannii infections in conflict and war zones: A global health challenge. Current Opinion in Infectious Diseases, 36 (6), 455-462.

Llewelyn, M. J., Budgell, E. P., and Laskawiec, D. (2023). The role of broad-spectrum antibiotics in the selection of bacterial resistance. The Lancet Infectious Diseases, 23 (1), e1-e9.

Médecins Sans Frontières (MSF). (2024). Gaza: No medicine, no food, no water: A man-made crisis. https://www.msf.org/gaza-no-medicine-no-food-no-water-man-made-crisis

Mendelson, M., Sharland, M., and Mpundu, M. (2023). Antibiotic resistance: A call to action. The Lancet Global Health, 11 (12), e1825-e1826.

O'Neill, J. (2016). Tackling drug-resistant infections globally: Final report and recommendations. The Review on Antimicrobial Resistance. https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf

Quesada, J. (2024, February 15). 'An impossible choice': Doctors in Gaza forced to leave patients to die. The Guardian. https://www.theguardian.com/world/2024/feb/15/gaza-doctors-impossible-choice-leave-patients-to-die

Truppa, C., Beyer, S., and Abo, J. (2019). Antimicrobial resistance in conflict settings: A systematic review. The Lancet Infectious Diseases, 19 (12), e407-e418.

UNICEF. (2024). Gaza humanitarian situation report. https://www.unicef.org/media/156361/file/Gaza-Humanitarian-Situation-Report-2024.pdf

World Health Organization (WHO). (2024a). WHO and partners scale up support to meet escalating health needs in Gaza. https://www.who.int/news/item/15-05-2024-who-and-partners-scale-up-support-to-meet-escalating-health-needs-in-gaza

World Health Organization (WHO). (2024b). Health resources and services availability monitoring system (HeRAMS) report: Gaza Strip. https://www.who.int/publications/m/item/health-resources-and-services-availability-monitoring-system-(herams)-report---gaza-strip

Ricos Biology Journal

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Published

31-10-2025

Data Availability Statement

Copyright: Copyrights retained to the Authors., Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/),which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/public domain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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How to Cite

A Perfect Storm: The Escalating Crisis of Antimicrobial Resistance in Surgical Wounds in Gaza: Antimicrobial Resistance in Gaza. (2025). Ricos Biology, 3(10), 13-16. https://doi.org/10.33687/ricosbiol.03.010.86

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